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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5722df93adf5248ed43273db69f0ad8e3ab3c5e4ccfd82d4d4de8f786486bb03' 
  AND token = 'xvJ0eWbsXPFLxHIGjXfPZtuT/Lt8tBx6+//z3Cxk9EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}