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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b34e18ef649227a50fbe9634cde20c27b435c2052f530e83f783afa43a01f94' 
  AND token = 'Ul28sUu2NmX3jv/cVittvbkP80B4aceolnbajhwKkKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}