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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82c3b26f96faaa0d5a90e39509dee97f6b89cd6d9a03f487d4256400972d90dc' 
  AND token = 'xLrDUrHHEIC4Dmi5TxldFrG+4fqRKW5DxUV86Sc0Lrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}