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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb250e6a729ec5ca8e1f16acc99768542a4c8afc2e90c447b9dfb21351547b7' 
  AND token = 'LiU79rk4gCpOs1CsMsLJ4cqMl49D1RABNYLi+zZ8BAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}