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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f580d1ae8afef62f4a256f60eecf53b0a4824d65c52f497aee904366b4d79066' 
  AND token = '/vGtFA0Lu9CQm53/TVNMwYfS5aDoYQ9HsBtsnKPtd5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}