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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb37b2d8c6090ca3ce5290c24597869ab25e6359b7a3d97302e259f42bd25b8' 
  AND token = '5dUgPJgs6HH22a5xxaL4h4GF1qMDMA745cItv8pMT+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}