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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a54943206254e1058db0877cc641849e457fb3dc8050f4b3b157cfbaed056e' 
  AND token = 'KRy0JLpxcpsJnvAS27qzraU+PEiA9AgeEWbsv7L6JZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}