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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4ece62d5637417c3addac85f1836e2cba7e828ced6f01a950cf63d84391d5a' 
  AND token = 'sDg0GiOdeZc+W7LH3txmFE+uucf70Ti7AZUEqhGMZew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}