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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '950b53ed6dc0124b9fe728e18af46c0efb0cc62a7bec1e1fa50ef44d9bf7e7af' 
  AND token = 'eJMUT9giOgnO1eV2YOrJ+ZO6T4NXhjppixdSfWITzpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}