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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0567ff4e3507e885a4f29c43869a778202949253325b969b9e3c282d9db7f8f' 
  AND token = 'DrPQIph1inaRcoD8pyo/zi+5dPd6vW3SEhAir+VH6BQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}