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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3080cdf9396d6fabb86cd1d41e4ed33fa4a7758671094cb7f60ee819bc5be66c' 
  AND token = 'gi8TXn9aHEIP/ZZWdw+2eShsLFrH51w8CG68rFB4tFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}