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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19e873e0b898e0513eab8cec2e1080c6651457787e3bcd76862e212cc7f4145d' 
  AND token = 'kWD3rjf0LCYP8+BYeAu2I0FwOXFyaV+rJi6+rjrhqYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}