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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6991abcb0e05ca724c80d25c8459a05d978dd7edccb4d3a113acd9228355893b' 
  AND token = 'cNlG1dYnjOpXvU4VWopRZXAhL2IZcY0oKaXAw3oai+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}