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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52717fc3d7a8674373d5207c3f25f65b780f0201ad928095783c573ff87678c' 
  AND token = 'hW7MrVIFxFvwpoL7d9YZsFkAkQWp3JIWfRPHJ8DQOmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}