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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55d86abceee4801a1b59c0066bd1cbe82f9e34fddf11ef3cfd88dcea741e380' 
  AND token = 'S6kJmH/QGPCQshwZ8LnWbcBP/Qtnw1b8jFDiJbWNmIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}