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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d533a7b7395f73b92bcb091cee8440d41020589b32a3038ed27d00ac0c364d7' 
  AND token = 'N63GOf2xvCbfTNdr7mCudKuYu/WOZ7D1NtPT2gp2Rco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}