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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c325a71675a67316a12e2575cef2075ce5fe62a67e63348d6f0b4fc66845611f' 
  AND token = 'aynBptypCn97BL0x0S+uwfh3I9MVqcybx98EC68uqmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}