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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16383d6db018d8be463fd50f780689c79b7b6379d7d018d61686819279c8dfda' 
  AND token = 'voFAgSNlmlv2S2mA/TcLgPd+RvOu911QzcUYUtDyopw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}