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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e4b36cb300316f1f2d7e06da5c5e85b530b51bfa66c5ff912f76edcd3875e2' 
  AND token = 'a+10AdWFRV8oi8rarasoIvqTyrwNH6AwTMwPMQtOAos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}