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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dbd2759fd5fb0dcc2ff2da440d5355c7b8cd24bec04c09daa0cb30b3fb6e409' 
  AND token = 'dbylYInjddVwiYpcNnaFkLMTC+xKBdCh3flpLRBCtyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}