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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '351d242f3c4963a55839ac65dd76445dcf40faab55aa92107da8ea13cf4a27a1' 
  AND token = 'Q7m+KG2zviGOL/uVOAInoAg6xaIzWDI1OjKygX7dEVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}