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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ac22505926d204ccbbee9f98ecea5a9d9c12e0f404d95c678c65016fd6c51e' 
  AND token = 'v5Os9MfQFiwnz03pkL5rbGiavg25XILEgEYyGUf+RUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}