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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee36335e270b03ac84a498c71ccc9000707a6341b2d990204b2870637e385f4c' 
  AND token = 'y0J29JkpDVlFJms54e6txPsHlVcUfN8+UaoWLAZIVpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}