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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '703b14107a8df6be23b5b5abdd40f401f74cabda9adc387854212e4aaabf3a44' 
  AND token = 'qaWm+z97/fXPXQwwGZeELZHOzWiZRUhjKYm9E90DmN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}