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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2684b233e5bced03bb608b17863a4451db3b26a8450ab2d22ab6fe57f4e3344a' 
  AND token = '8eUiZXaijJ5Yw4aMdWaG3fuwkZLPYUaKAlqxyQmnPmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}