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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50419d379c701c0dc1ba6e401e133abc93098f29aea1ead63220db461979b09' 
  AND token = 'CTENkIVZkz+BTN6PD8r51B8bstJ79AGNMT5fJy+IMtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}