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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7300112d6d10a072d1d294647d8190435bac3586e61b5c8c4587adee74ef2e58' 
  AND token = 'ADSwfB309ExUoltjcejJNMcrHygf+iagbdEFyn6yMXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}