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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7eb467d30c5dfa80ad5fe54cc3214fb3fe2549d445507d54d160d8bfe9e838' 
  AND token = '9SpgBQ+RTo4K9lb80XMiN1H0W/4jVdtjGX4qfSYDsjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}