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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56b05c37a4d3316716cb6838cbea077ae1ac44e53dcec4cfbeec4a3af46c3570' 
  AND token = 'l0ibdqbCH2Q/Bu5cO+Xe90nXcI6QdXsw6lfn044HkOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}