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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00006283927dd3f549fc4483b26eba988e5d106c7845a60883ceb2e4d03289f2' 
  AND token = 'mybD4mFsJ842FaySUXAAizkYDgn+Mt5kDOY17xcrHvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}