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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89a91e48b161e5084329b2469a78fadfd86a89012fb7ad1680412428ee3f19b9' 
  AND token = 'zpcctoeoGG8JVtC9hKZ3M+TYXroXnQXSIhs9N5Ki64E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}