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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6fdddb60bd78fafcc4bc9e5573e554f93e0b237be2a18c09feada4117ef180' 
  AND token = 'H4S6OrRPI62bIC0VnmIAUfZuhz5kyRmQILMauIoW0/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}