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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd640f893fb199fe2b15bea2baf535c36d010c3fb40ebe5aa9ef93d5e1e7c268' 
  AND token = 'nd8ir4xzO+LLYkzsd+mkaaW/Bvj8cR/X4JeKnTpbai0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}