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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4def7d73f656870f15ac7633719fc1f9edee5e31d113b99c53ba5bf1d559dc0f' 
  AND token = 'BsbDAkHrO+q0VXr8AlPTET7+RwmwdRB5vdZe/D7W6n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}