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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be31f4b67aa36667f08be206a0c6fbde906e1f1a2d680a06449b3cb939dff067' 
  AND token = '8PiMpw1YG6o30JB8I3Doy2CGDY/3GiE9VCHhaxpNseY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}