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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e367add0eb244d2b6fa0651b068f8b9c7b88bfe0eaf12650c8981466ad5bb7c6' 
  AND token = 'eJbJH5dM2MDQ0loP6Th1SioeoK51mHmIMJyOPGSGcdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}