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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97e689ab7aebe0fe3ddc14fca78778c62c7ce3aabd371642c607185a90405543' 
  AND token = 'e3ML8yvkxLsesA/XOZvXF/kONL58LCDrnrOCDEfF4SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}