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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ceaa37952210720fc15672258e7ed384d96048f5a659ee04901f0aca00c4472' 
  AND token = 'jjncMjaT5NY1yDzxVbMGsIj1Mo1PcxKBr54+Dyyvww0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}