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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71664767f8d975e2cf2284ebb6f12f74bbce317aa9af6744c4d45550cf312974' 
  AND token = 'YZ1s2leRryObI28W1AcpcV0uduImzVUMkfLqajbkZ0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}