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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a1fc82019afd19d3530546136ad26369a88a5826deebae1a5061945e3efe94' 
  AND token = 'FyD3JDTJRPUg1Ih91IpK4pg7fRlq59N0Eg5iugmW5cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}