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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d5dd8452b98d877196171d716f0add4be7fb97bc9fdb4c59355e2aff384488' 
  AND token = 'YnQkkKh+BdHU8Ee4JYxwBytnEJHeEyMfQm1PWWeXABo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}