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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fdd699fa31762098a023847acf2e5c00a76777b5da4dfcebb1c08212f1a5cb5' 
  AND token = '7j8SH/g302mKk/w57v1Job2okuE+hscKJdeKaqhP244=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}