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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54f202b3da3a519ada56904da1c9832b403a846c0ac6d17d81d6aabfea26398' 
  AND token = 'ce9Iww58/OYtnTs+tJAmYPQfIyPIAcH6QEwD+UvgZQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}