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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016fd723bbf7e52d5fb72d4a2c36b899737573397b3802612e44a698a14f68a6' 
  AND token = 'PB9WzRyncDiUJsDK4Lwrd4I9MPXt6rt7ByCuaQoam04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}