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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f4e22162bd57d7a957d96c804c26fb81894b225a56320abcc002a6fb171ab2' 
  AND token = 'Q4e6EZZF0hARSdkzPAvIEtVBBt0EO2rGcczGyzt83Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}