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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f91c5011e84a7d3d348f1b998bb4ab95464afb0bcd04423063b5d62189f318d2' 
  AND token = 'UuxWl6lMFxdfyye/BO9uzqfOz9TpQ89FcgUc8xX0n+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}