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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5a8e7c3eb54535ded6b7d6e56126fe9b123402fc70dc9980b364b013145faeb' 
  AND token = 'C5z0L/nT7cB1gyYiXs5nRZs2tT6d/lDU/pcTK1kwKjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}