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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9353cc963f67f6072c0b9ea2b65e9e202ee19683829e3c0cb1be3b783b70c996' 
  AND token = 'iojUZ8m5QmkgYHvPW6xCPeGykDIuUa7Kvhqd8xBhPcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}