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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0dcc9db8c7c3ef9fe86c88afbf06d26d4e58a29c40620fb0116d56d3a77a35' 
  AND token = 'l1h+wtTrVI/sx4ihDF42zUwwkE5NnoGiSfgyZiz0eq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}