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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4578a8b908aad24598a8f298b1578c4c46cbf693a3e6d9d7c89a906bfafdb7ec' 
  AND token = '7HMt1bXjtYN3M8jcMD4K6A8c13Hd5KPKfLdrXBKF9vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}